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Table 1 Demographic and laboratory characteristics of patients with hepatitis A on admission (A), 2 weeks after admission (B), and controls

From: Mean platelet volume in children with hepatitis A

    

p value

Characteristics

Healthy controls

A

B

Control vs. A

Control vs. B

A vs. B

Number of patients

62

62

62

   

Age, years

9.1 ± 4.3

9.6 ± 3.6

9.6 ± 3.6

   

Male/female ratio

30/32

30/32

30/32

   

WBC (count/mm3)a

7800 (4800–11,000)

5440 (2100–27,400)

7197 (3900–6200)

0.023

0.021

NS

Platelet counts (count × 103/mm3)a

336 (176–967)

278 (22–748)

298 (69–554)

NS

NS

0.042

MPV (fL)

8.28 ± 1.13

9.47 ± 1.62

8.84 ± 1.48

<0.0001

<0.0001

0.005

AST (IU/L)a

27(11–33)

927 (34–4145)

33 (16–519)

<0.0001

0.004

<0.0001

ALT (IU/L)a

14 (6–36)

1250 (36–4113)

35 (6–1358)

<0.0001

<0.0001

<0.0001

T. bil (IU/L)a

1 (0.3–17.2)

    

D. bil(IU/L)a

0.67 (0.1–7.7)

    

PTT

29.1 (18.1–46.9)

    

PT

13.7 (10.7–35.1)

    
  1. Parametric values were expressed as means with standard deviation. Significance was determined by p < 0.05
  2. AST aspartate transaminase, ALT alanine transaminase, PT prothrombin time, aPTT activated partial thromboplastin time, MPV mean platelet volume, WBC white blood cell, T.bil total bilirubin, D.bil direct bilirubin, NS not significant
  3. aIf not normally distributed, values were presented as median (minimum-maximum)