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Table 1 Demographic and laboratory characteristics of patients with hepatitis A on admission (A), 2 weeks after admission (B), and controls

From: Mean platelet volume in children with hepatitis A

     p value
Characteristics Healthy controls A B Control vs. A Control vs. B A vs. B
Number of patients 62 62 62    
Age, years 9.1 ± 4.3 9.6 ± 3.6 9.6 ± 3.6    
Male/female ratio 30/32 30/32 30/32    
WBC (count/mm3)a 7800 (4800–11,000) 5440 (2100–27,400) 7197 (3900–6200) 0.023 0.021 NS
Platelet counts (count × 103/mm3)a 336 (176–967) 278 (22–748) 298 (69–554) NS NS 0.042
MPV (fL) 8.28 ± 1.13 9.47 ± 1.62 8.84 ± 1.48 <0.0001 <0.0001 0.005
AST (IU/L)a 27(11–33) 927 (34–4145) 33 (16–519) <0.0001 0.004 <0.0001
ALT (IU/L)a 14 (6–36) 1250 (36–4113) 35 (6–1358) <0.0001 <0.0001 <0.0001
T. bil (IU/L)a 1 (0.3–17.2)     
D. bil(IU/L)a 0.67 (0.1–7.7)     
PTT 29.1 (18.1–46.9)     
PT 13.7 (10.7–35.1)     
  1. Parametric values were expressed as means with standard deviation. Significance was determined by p < 0.05
  2. AST aspartate transaminase, ALT alanine transaminase, PT prothrombin time, aPTT activated partial thromboplastin time, MPV mean platelet volume, WBC white blood cell, T.bil total bilirubin, D.bil direct bilirubin, NS not significant
  3. aIf not normally distributed, values were presented as median (minimum-maximum)