Table 2 Antimicrobial susceptibility profile of various species of Shigella (2003–2015)
From: Shigellosis in Nepal: 13 years review of nationwide surveillance
N (%) resistance to | ||||||||
|---|---|---|---|---|---|---|---|---|
Year | Species | Number tested | Ampicillin | Ciprofloxacin | Nalidixic acid | Cotrimoxazole | Mecillinam | Ceftriaxone |
2003 | S. dysentriae | 13 | 11 (85) | 8 (62) | 10 (77) | 9 (69) | 5 (38) | 0 |
S. flexneri | 7 | 7 (100) | 0 | 0 | 6 (86) | 2/6 (33)a | 0 | |
S. boydii | 3 | 2 (66) | 0 | 1 (33) | 2 (66) | 2 (66) | 0 | |
S. sonnei | 2 | 1 (50) | 0 | 2 (100) | 2 (100) | 1 (50) | 0 | |
2004 | S. dysentriae | 28 | 25 (89) | 13 (46) | 14 (50) | 18 (64) | 20/27 (74)a | 0 |
S. flexneri | 12 | 9 (75) | 6 (50) | 6 (50) | 8 (67) | 4 (33) | 0 | |
S. boydii | 2 | 1 (50) | 0 | 0 | 1 (50) | 0 | 0 | |
S. sonnei | 2 | 0 | 0 | 2 (100) | 2 (100) | 0 | 0 | |
2005 | S.dysentriae | 10 | 8 (80) | 6/9 (66)a | 7 (70) | 8 (80) | 2/8 (25)a | 0 |
S. flexneri | 31 | 18/30 (60)a | 0 | 17/28 (59)a | 21 (68) | 13 (42) | 0 | |
S. boydii | 6 | 4 (66) | 0 | 3 (50) | 0 | 4 (66) | 0 | |
S. sonnei | 4 | 1 (25) | 0 | 2 (50) | 2 (50) | 0 | 0 | |
2006 | S. dysentriae | 6 | 4/5 (80)a | 0 | 4/5 (80)a | 2/5 (40)a | 4 (66) | 0 |
S. flexneri | 14 | 8/13 (62)a | 3/12 (25)a | 4/10 (40)a | 7/12 (58)a | 14 (100) | 0 | |
S. boydii | 2 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. sonnei | 1 | S | R | R | S | S | S | |
2007 | S. dysentriae | 10 | 5/6 (83)a | 4 (40) | 2 (20) | 2 (20) | 10 (100) | 0 |
S. flexneri | 22 | 17/21 (81)a | 12/21 (57)a | 21 (95) | 19/21 (90)a | 22 (100) | 2/20 (10)a | |
S. boydii | 3 | 3 (100) | 0 | 0 | 0 | 3 (100) | 0 | |
S. sonnei | 2 | 0 | 0 | 0 | 0 | 2 (100) | 0 | |
2008 | S. dysentriae | 2 | 0 | 2 (100) | 2 (100) | 0 | 2 (100) | 0 |
S. flexneri | 8 | 8 (100) | 3/5 (60)a | 8 (100) | 4/5 (80)a | 8 (100) | 0 | |
S. sonnei | 2 | 2 (100) | 0 | 2 (100) | 0 | 2 (100) | 0 | |
Shigella spp. | 5 | 3 (60) | 1/4 (25)a | 2/4 (50)a | 3/4 (75)a | 5 (100) | 1/3 (33)a | |
2009 | S. dysentriae | 8 | 8 (100) | 2 (25) | 7 (88) | 7 (88) | 8 (100) | 0 |
S. flexneri | 6 | 4/5 (80)a | 6 (100) | 4/5 (80)a | 6 (100) | 6 (100) | 2 (33) | |
S. sonnei | 1 | R | S | R | S | R | S | |
Shigella spp. | 5 | 3 (60) | 3 (60) | 4 (80) | 4 (80) | 5 (100) | 2 (40) | |
2010 | S. dysentriae | 5 | 5 (100) | 1 (20) | 5 (100) | 5 (100) | – | 0 |
S. flexneri | 4 | 4 (100) | 1 (25) | 4 (100) | 4 (100) | – | 0 | |
Shigella spp. | 1 | R | S | R | R | – | S | |
2011 | S. dysentriae | 2 | 2 (100) | 1 (50) | 1 (50) | 2 (100) | – | 0 |
S. flexneri | 5 | 3 (60) | 0 | 0 | 3/4 (75)a | – | 0 | |
S. sonnei | 2 | 1 (50) | 0 | 2 (100) | 0 | – | 0 | |
Shigella spp. | 2 | 2 (100) | 0 | 2 (100) | 2 (100) | – | 0 | |
2012 | S. dysentriae | 4 | 4 (100) | 0 | 3 (75) | 3 (75) | – | 0 |
S. flexneri | 7 | 7 (100) | 4/6 (66)a | 3/4 (75)a | 4/6 (67)a | – | 2/6 (33)a | |
S. sonnei | 3 | 0 | 0 | 1 (33) | 3 (100) | – | 0 | |
2013 | S. dysentriae | 5 | 5 (100) | 0 | 4 (80) | 3 (60) | – | 0 |
S. flexneri | 19 | 15/16 (93)a | 12/17 (71)a | 16/18 (89)a | 14 (74) | – | 5/18 (27)a | |
S. sonnei | 3 | 3 (100) | 2 (66) | 2 (66) | 2 (66) | – | 0 | |
Shigella spp. | 3 | 3 (100) | 0 | 3 (100) | 3 (100) | – | 0 | |
2014 | S. dysentriae | 1 | S | R | S | S | – | S |
S. flexneri | 12 | 7/11 (64)a | 8 (66) | 11 (92) | 7 (58) | – | 0 | |
S. sonnei | 5 | 3 (60) | 5 (100) | 5 (100) | 5 (100) | – | 0 | |
S. boydii | 1 | S | R | R | R | – | S | |
Shigella spp. | 6 | 6 (100) | 1/5 (20)a | 3/4 (75)a | 3 (50) | – | 0 | |
2015 | S. dysentriae | 3 | 0 | 0 | 3 (100) | 2 (75) | – | 0 |
S. flexneri | 19 | 16/18 (88)a | 9 (47) | 15 (79) | 17 (89) | – | 3 (16) | |
S. sonnei | 4 | 3 (75) | 4 (100) | 4 (100) | 4 (100) | – | 0 | |
Shigella spp. | 1 | R | S | R | R | – | S | |