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Table 4 Risk (odds ratio with 95% CI) of adverse pregnancy outcomes and maternal complication by sickle cell disease status

From: Sickle cell disease and pregnancy outcomes: a study of the community-based hospital in a tribal block of Gujarat, India

 

Negative (Ref) vs. SCD

Negative (Ref) vs. sickle cell trait

Sickle cell trait (Ref) vs. SCD

Spontaneous abortion

0.78 (0.43–1.39)

1.09 (0.78–1.22)

0.71 (0.39–1.30)

Stillbirth

3.45 (1.92–6.21)**

1.41 (1.09–1.85)*

2.43 (1.31–4.53)**

Blood transfusion

37.66 (26.08–54.39)**

1.46 (1.11–1.91)**

25.88 (16.99–39.41)**

Severe anaemia

1.28 (0.87–1.88)

1.05 (0.93–1.41)

1.22 (0.82–1.82)

Any anaemic

13.84 (1.93–99.51)**

0.85 (0.71–1.00)

16.39 (2.28–117.92)**

Severely low birth weight ≤1499

2.07 (1.11–3.87)*

1.09 (0.85–1.41)

1.89 (0.98–3.66)

Low birth weight ≤2499

3.01 (2.06–4.39)**

1.01 (0.90–1.11)

2.99 (2.03–4.41)**

Pre-term delivery (gestational weeks ≤36 weeks)

3.88 (2.73–5.51)**

0.98 (0.85–1.13)

3.96 (2.74–5.72)**

Caesarean section

3.79 (2.31–6.21)**

0.86 (0.68–1.08)

4.42 (2.60–7.52)

Intrauterine growth retardation (IUGR)

1.44 (0.45–5.46)

1.15 (0.78–1.71)

1.25 (0.38–4.14)

Pregnancy-induced hypertension (PIH)

0.73 (0.36–1.51)

0.99 (0.82–1.20)

0.74 (0.35–1.55)

Eclampsia

2.18 (0.68–6.97)

0.98 (0.58–1.65)

2.22 (0.64–7.69)

  1. Ref reference category
  2. *P < 0.05; **P < 0.01