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Table 5 Correlation between phenotypic and genotypic resistance pattern of the DEC isolates (n = 67)

From: A study of virulence and antimicrobial resistance pattern in diarrhoeagenic Escherichia coli isolated from diarrhoeal stool specimens from children and adults in a tertiary hospital, Puducherry, India

Antimicrobial class

Antimicrobials

AMR genes detected

Pattern 1

Pattern 2

Pattern 3

Pattern 4

Quinolones

Ciprofloxacin and levofloxacin

qnrB, qnrS, aac(6′)-Ib

13 (19.4%)

20 (29.8%)

9 (13.4%)

25 (37.3%)

Aminoglycosides

Amikacin and gentamicin

aac3, aadB

42 (62.6%)

9 (13.4%)

9 (13.4%)

7 (10.29%)

Tetracycline

Tetracycline

tetA, tetB. tetD

25 (37.3%)

13 (19.4%)

18 (23.8%)

11 (16.4%)

Phenicols

Chloramphenicol

cat1

44 (65.6%)

6 (8.9%)

12 (17.9)

5 (7.4%)

β-lactam

Ceftazidime, ceftriaxone, and cefoperazone-sulbactam

blaCTX, blaTEM, blaSHV

15 (22.5%)

16 (23.8%)

13 (19.4%)

23 (34.3%)

Trimethoprim and sulfonamide

Co-trimoxazole

sul1, sulII, sulIII, dhfr1

9 (13.4%)

1 (1.4%)

28 (41.7%)

29 (43.2%)

  1. Pattern 1: No resistance gene(s) detected and phenotypically sensitive
  2. Pattern 2: No resistance gene(s) detected but phenotypically resistant
  3. Pattern 3: Resistance gene(s) detected but phenotypically sensitive
  4. Pattern 4: Resistance gene(s) detected and phenotypically resistant