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Table 2 Biochemical parameters for all types of therapies—DPP4I study, Anuradhapura 2017

From: Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka

Investigation

OOH group (n = 126)

DPP4I group (n = 63)

Estimated difference of means (95% CI)

p value*

Median (IQR)

Mean (SD)

Median (IQR)

Mean (SD)

eGFR (ml/min/1.73m2)

88.5 (73–101)

88.2 (17.0)

88 (71–98)

85.9 (16.4)

− 2.3 (− 7.4 to 2.8)

0.379

HbA1C (%)

8.4 (7–10)

8.8 (1.9)

8.5 (7–10)

8.6 (1.8)

−2.0 (−0.8 to 0.4)

0.569

Pancreatic amylase (U/L)

36 (27–48)

44.8 (57.1)

38 (32–55)

47 (27.1)

2.2 (−12.8 to 17.2)

0.171

Serum lipase (U/L)

45 (35–60)

48.6 (18.6)

52 (42–73)

69.9 (67.2)

21.3 (8.6 to 34.0)

0.012

AST (U/L)

23 (17–30)

26.4 (18.4)

25 (20–32)

28.3 (15.9)

1.9 (−3.5 to 7.3)

0.238

ALT (U/L)

22 (15–33)

26 (15.5)

24 (16–34)

29.9 (19.9)

3.9 (−1.3 to 9.1)

0.347

  1. CI confidence interval, DPP4I dipeptidyl peptidase 4 inhibitors, IQR interquartile range, OOH other oral hypoglycaemics
  2. *Mann-Whitney U test was performed