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Table 3 Biochemical parameters for dual therapies—DPP4I study, Anuradhapura 2017

From: Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka

Investigation

OOH group (n = 123)

DPP4I group (n = 07)

Estimated difference of means (95% CI)

p value*

Median (IQR)

Mean (SD)

Median (IQR)

Mean (SD)

HbA1C (%)

8.4 (7–10)

8.8 (1.9)

7.5 (7–8)

7.7 (1.2)

− 1.1 (−2.5 to 0.3)

0.110

Pancreatic amylase (U/L)

36 (27–48)

44.3 (57.6)

58 (32–97)

60.1 (33.1)

15.8 (−27.8 to 59.4)

0.095

Serum lipase (U/L)

45 (35–60)

48.7 (18.8)

60 (52–148)

91.6 (48.1)

42.9 (26.7 to 59.1)

0.007

AST (U/L)

23 (17–29)

26.2 (18.5)

23 (22–28)

24.1 (7.2)

− 2.1 (−16.0 to 11.8)

0.912

ALT (U/L)

22 (15–33)

26.1 (15.5)

24 (18–29)

23.4 (7.6)

−2.7 (−14.4 to 9.0)

0.992

  1. CI confidence interval, DPP4I dipeptidyl peptidase 4 inhibitors, IQR interquartile range, OOH other oral hypoglycaemics
  2. *Mann-Whitney U test was performed