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Table 3 Stratified analysis of the effects of web-based interventions on weight loss

From: Obesity paradigm and web-based weight loss programs: an updated systematic review and meta-analysis of randomized controlled trials

Variable

Num. of data

Mean difference (95% CI), kg

I2

P heterogeneity

Significance

Meta-regression

Mean age

 < 45

3

4.19 (1.89–6.49)

84.7

0.001

0.000

Referent

 ≥ 45

4

− 0.06 (− 4.21–4.08)

0.0

0.46

0.97

0.55

Not described

1

− 3.11 (− 6.6–0.46)

0.088

 

Duration

 24 months

2

− 0.40 (− 7.58–6.78)

0

0.49

0.91

Referent

 16 months

2

6.82 (4.01–9.63)

62.6

0.102

0.000

0.50

 12 months

4

− 1.69 (− 4.04–0.65)

16.5

0.31

0.15

0.46

Use of intent-to-treat analysis

 No

1

− 3.1 (− 6.6–0.46)

0

0.088

Referent

 Yes

7

3.19 (1.18–5.21)

68

0.005

0.002

0.005

Interactive web-based intervention

 No

4

− 1.35 (− 4.08–1.36)

25.3

0.26

0.33

Referent

 Yes

4

3.81 (1.53–6.1)

80.9

0.001

0.001

0.27

Drop-out rate

 < 20%

7

1.97 (0.14–3.81)

77.5

0.001

0.03

Referent

 ≥ 20%

1

− 1.5 (− 7.48–4.81)

0

0.62

0.77

Included feedback in web-based intervention content

No

3

3.37 (1.21–5.54)

90.2

0.000

0.002

Referent

Yes

5

− 1.54 (− 4.52–1.43)

0

0.96

0.31

0.83

Included goal-setting in web-based intervention content

 No

4

2.79 (0.62–4.96)

86.5

0.001

0.012

Referent

 Yes

4

− 0.38 (− 3.3–2.57)

0.0

0.43

0.79

0.56

Jadad score

 < 2

4

2.58(0.53–4.63)

86.5

0.001

0.014

Referent

 ≥ 2

4

− 0.75 (− 4.11–2.61)

0

0.41

0.66

0.27

Country

 Others

3

− 2.37 (− 4.83–0.09)

0

0.85

0.049

Referent

 USA

5

5.80 (3.32–8.29)

38.80

0.16

0.001

0.004