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Table 3 Association between inflammatory markers and polyphenol intakes (mg/day) and (ml/day) over quartiles of polyphenol intake (n = 391)

From: Inflammatory biomarkers in overweight and obese Iranian women are associated with polyphenol intake

Polyphenol intakes (mg/day)

Variables

Q2

Q3

Q4

 

β (SE)

95%CI

P value

β (SE)

95%CI

P value

β (SE)

95%CI

P value

P-trend

Inflammatory factors

Hs-CRP (mg/l)

Crude

0.118 (0.642)

− 1.142, 1.378

0.854

− 0.316 (0.644)

− 1.579, 0.947

0.623

− 0.807 (0.638)

− 2.057, − 0.044

0.046

0.147

Model 1

0.180 (0.755)

− 1.301, 1.66

0.811

− 0.777 (0.733)

− 2.215, 0.661

0.069

− 0.415 (0.763)

− 1.912, 1.082

0.587

0.352

PAI-1 (mg/dL)

Crude

0.231 (4.263)

− 8.126, 8.587

0.957

− 0.173 (4.274)

− 8.550, 8.205

0.968

− 2.999 (4.232)

− 11.295, 5.296

0.479

0.068

Model 1

3.025 (5.222)

− 7.211, 13.260

0.562

− 1.622 (5.071)

− 11.562, 8.317

0.749

− 4.503 (5.279)

14.851, 5.845

0.394

0.291

MCP-1 (mg/dL)

Crude

− 7.675 (13.060)

− 33.272, 17.923

0.557

− 13.540 (13.092)

− 39.202, 10.122

0.061

− 8.311 (12.964)

− 33.722, 17.099

0.521

0.470

Model 1

− 3.414 (15.897)

− 34.573, 27.745

0.830

− 15.034 (15.438)

− 25.292, 9.224

0.070

− 10.665 (16.072)

− 42.167, 20.836

0.507

0.387

TGF-β (mg/dL)

Crude

− 2.462 (6.916)

− 16.017, 11.094

0.722

1.311 (6.933)

− 12.279, 14.900

0.850

4.132 (6.865)

− 9.324, 17.589

0.547

0.439

Model 1

− 12.700 (10.065)

− 32.429, 7.028

0.207

− 11.695 (9.510)

− 30.335, 6.945

0.219

− 8.355 (9.003)

− 26.003, 9.292

0.353

0.968

IL-1 β (mg/dL)

Crude

− 0.129 (0.138)

− 0.399, 0.142

0.351

− 0.173 (0.138)

− 0.444, 0.099

0.212

0.044 (0.137)

− 0.225, 0.312

0.750

0.782

Model 1

− 0.53 (0.165)

− 0.378, 0.272

0.750

− 0.148 (0.161)

− 0.464, 0.168

0.358

0.125 (0.167)

− 0.204, 0.453

0.458

0.652

Gal-3 (ng/ml)

Crude

− 0.167 (0.809)

− 1.753, 1.419

0.837

− 0.509 (0.811)

− 2.099, 1.08

0.530

− 0.519 (0.803)

− 2.093, 1.055

0.518

0.456

Model 1

0.097 (0.980)

− 1.825, 2.019

0.921

− 0.706 (0.952)

− 2.572, − 0.161

0.049

− 0.726 (0.991)

− 2.669, 1.218

0.464

0.340

Ghrelin (pg/ml)

Crude

0.122 (0.258)

− 0.384, 0.629

0.636

− 0.008 (0.259)

− 0.516, 0.500

0.975

− 0.242 (0.256)

− 0.745, 0.261

0.347

0.271

Model 1

0.215 (0.317)

− 0.408, 0.838

0.498

− 0.063 (0.308)

− 0.668, 0.542

0.839

− 0.278 (0.321)

− 0.908, 0.352

0.387

0.291

Leptin (ng/ml)

Crude

1.078 (1.875)

− 2.599, 4.755

0.565

− 1.053 (1.880)

− 4.739, 2.633

0.576

− 0.468 (1.862)

− 4.118, 3.182

0.802

0.536

Model 1

0.413 (2.299)

− 4.093, 4.920

0.857

− 1.67 (2.232)

− 6.047, 2.704

0.454

− 0.457 (2.324)

− 5.012,4.099

0.844

0.624

Polyphenol intakes (ml/day)

Hs-CRP (mg/l)

Model 1

− 0.144 (0.743)

− 1.601, 1.313

0.846

0.577 (0.743)

− 0.880, 2.035

0.438

0.406 (0.778)

− 1.120, 1.933

0.602

0.424

PAI-1 (mg/dL)

Model 1

− 2.841 (5.148)

− 12.932, 7.249

0.581

− 1.491 (5.149)

− 11.585, 8.602

0.772

− 2.424 (5.392)

− 12.993, 8.144

0.653

0.724

MCP-1 (mg/dL)

Model 1

− 5.786 (15.629)

− 36.419, 24.848

.0711

4.665 (15.634)

− 25.977, 35.307

0.765

− 8.838 (16.370)

− 40.923, 23.247

0.589

0.777

TGF-β (mg/dL)

Model 1

3.046 (7.184)

− 11.034, 17.126

0.672

− 1.059 (7.186)

− 15.143, 13.026

0.883

5.005 (7.524)

− 9.742, 19.753

0.506

0.664

IL-1 β (mg/dL)

Model 1

− 0.126 (0.163)

− 0.446, 0.194

0.441

− 0.135 (0.1633)

− 0.455, 0.185

0.407

0.058 (0.171)

− 0.277, 0.393

0.734

0.809

Gal-3 (ng/mL)

Model 1

− 0.186 (0.965)

− 2.078, 1.706

0.847

0.225 (0.965)

− 1.667, 2.118

0.816

− 0.395 (1.010)

− 2.376, 1.587

0.696

0.826

Ghrelin (pg/ml)

Model 1

− 0.208 (0.313)

− 0.822, 0.406

0.506

− 0.170 (0.313)

− 0.784, 0.445

0.588

.021 (0.328)

− 0.623, 0.664

0.950

0.953

Leptin (ng/ml)

Model 1

0.317 (2.262)

− 4.118, 4.752

0.889

0.688 (2.263)

− 3.748, 5.124

0.761

− 0.005 (2.369)

− 4.650, 4.640

0.998

0.942

  1. Model 1: Adjusted for age, BMI, physical activity, total energy intake, supplements intake, and economic status, education (BMI was considered as a collinear variable)
  2. Logistic regression was used
  3. T1 was considered as the reference group
  4. Bold: P value < 0.05 was considered significant; also, 0.05, 0.06, and 0.07 were considered marginally significant. P trend < 0.05 was considered significant; also 0.05, 0.06, and 0.07 were considered marginally significant
  5. hs-CRP High-sensitivity C-reactive protein; IL-1β Interleukin-1 beta; Gal-3 Galectin 3; MCP-1 Monocyte chemoattractant protein-1; PAI-1 Plasminogen activator inhibitor-1; TGF-β Transforming growth factor
  6. *P value obtained from the adjusted model. All of the P values obtained from the analysis of the linear regression