Investigation of the association between the TCF7L2 rs7903146 (C/T) gene polymorphism and obesity in a Cameroonian population: a pilot study

Table 3 Stratification of clinical and biological parameters among genotypes

Characteristic	CX (CC + CT) n = 12	TT n = 90	p value
W/H ratio	0.84 (0.81–0.87)	0.83 (0.78–0.89)	0.65
SBP (mmHg)	123 (116.5–132.5)	120 (107–135)	0.42
DBP (mmHg)	75.5 (69–81.5)	75.5 (67–85)	0.89
BMI (kg/m²)	30.1 (23.7–31)	24.4 (21.8–32.8)	0.66
FBG	95.5 (88–107)	92.5 (85–102)	0.29
TC (mg/dL)	195.5 (189.5–222.1)	179.8 (164.7–198.4)	0.02
TG (mg/dL)	135.2 (121.6–158.4)	130.1 (121.1–142.5)	0.38
HDL-C (mg/dL)	44 (42–50.8)	47 (44.7–50.2)	0.28
LDL-C (mg/dL)	122.9 (118.1–148.3)	103.5 (94.6–118.4)	0.01

The results are expressed in median (interquartile range)
W/H ratio ratio of waist to hip circumference, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, FBG fasting blood glucose, TC total cholesterol, HDL-C HDL cholesterol, LDL-C LDL cholesterol, TG triglycerides

ISSN: 2072-1315