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Table 2 The association between serum iron and ALT

From: Association between serum iron and liver transaminases based on a large adult women population

 

Model 1, β (95% CI)

Model 2, β (95% CI)

Model 3, β (95% CI)

Iron (ug/dL)

0.015 (0.009, 0.020)***

0.026 (0.020, 0.032)***

0.026 (0.020, 0.031)***

Quartiles of iron

 Q1 (lowest quartile)

Reference

Reference

Reference

 Q2

1.428 (0.854, 2.003)***

1.435 (0.869, 2.002)***

1.415 (0.849, 1.981)***

 Q3

1.667 (1.099, 2.235)***

2.095 (1.529, 2.661)***

2.051 (1.485, 2.617)***

 Q4

1.598 (1.040, 2.155)***

2.575 (2.007, 3.143)***

2.540 (1.972, 3.108)***

 P for trend

 < 0.001***

 < 0.001***

 < 0.001***

Stratified by age (years) #

 18–24

− 0.003 (− 0.016, 0.010)

0.013 (− 0.000, 0.026)

0.013 (− 0.000, 0.026)

 25–34

0.001 (− 0.015, 0.016)

0.014 (− 0.002, 0.030)

0.015 (− 0.002, 0.031)

 35–44

0.005 (− 0.008, 0.018)

0.019 (0.006, 0.032)**

0.019 (0.006, 0.032)**

 45–54

0.049 (0.034, 0.063)***

0.062 (0.047, 0.076)***

0.061 (0.047, 0.076)***

 ≥ 55

0.026 (0.018, 0.035)***

0.032 (0.024, 0.041)***

0.032 (0.023, 0.040)***

Stratified by race #

 Mexican American

0.005 (− 0.017, 0.028)

0.027 (0.004, 0.050)*

0.027 (0.005, 0.050)*

 Other Hispanic

0.035 (0.010, 0.060)**

0.045 (0.020, 0.070)***

0.044 (0.019, 0.069)***

 Non-Hispanic White

0.009 (0.002, 0.017)*

0.023 (0.015, 0.030)***

0.022 (0.014, 0.030)***

 Non-Hispanic Black

0.029 (0.019, 0.039)***

0.030 (0.019, 0.040)***

0.029 (0.019, 0.040)***

 Other Races

0.024 (0.012, 0.037)***

0.035 (0.022, 0.048)***

0.034 (0.021, 0.046)***

  1. Bold indicates a statistical difference. *P < 0.05, **P < 0.01, ***P < 0.001. Model 1 was not adjusted. Model 2 was adjusted for age, race, education, family income-poverty ratio, pregnancy status, BMI, alcohol drinking, smoking exposure, cholesterol, glucose, triglycerides, and work activity. Model 3 was adjusted for model 2 plus histories of HBP, diabetes, and CKD. # In the subgroup analyses stratified by age and race, the models were not adjusted for the stratification variables themselves
  2. ALT alanine aminotransferase, BMI body mass index, HBP high blood pressure, CKD chronic kidney disease