Fig. 4

Intracellular Mg deprivation induces oxidative stress including malfunction in mitochondria [40]. ATP indicates adenosine triphosphate; ETC, electron transport chain; F0F1-ATPases, membrane-bound ATP synthases; IMAC, inner membrane anion channel; KATP, ATP-sensitive K channel; MnSOD, manganese superoxide dismutase; MRS2, mitochondrial RNA splicing 2; PTP, permeability transition pore; ROS, reactive oxygen species; VDAC, voltage-dependent anion channel