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Table 5 Analysis of maternal risk factors for low birthweight and macrosomia (N = 356)

From: Maternal risk factors for low birthweight and macrosomia: a cross-sectional study in Northern Region, Ghana

Characteristics

Multinomial logistic regression (Normal birthweight = base outcome)

Low birthweight

Macrosomia

COR

p value (95% CI )

AOR

p value (95% CI )

COR

p value (95% CI )

AOR

p value (95% CI )

Ethnicity

        

Dagomba

   

[Reference]

   

[Reference]

Frafra/Grusi

2.471

0.091 (1.327–4.603)

1.231

0.679 (0.460–3.298)

2.001

0.144 (0.789–5.078)

1.207

0.811 (0.258–5.642)

Others††

0.174

0.004 (0.023–1.326)*

0.104

0.039 (0.011–0.995)*

0.886

0.876 (0.194–4.048)

0.795

0.821 (0.109–5.817)

Religion

        

Christianity

   

[Reference]

   

[Reference]

Islamism

0.440

0.023 (0.217–0.893)*

0.389

0.119 (0.118–1.277)

0.430

0.094 (0.160–1.155)

0.471

0.348 (0.098–2.265)

Household fuel

        

Firewood

   

[Reference]

   

[Reference]

Charcoal

1.466

0.164 (0.855–2.513)

0.891

0.802 (0.360–2.201)

2.094

0.125 (0.814–5.391)

0.801

0.766 (0.187–3.431)

Gas

0.893

0.809 (0.356–2.238)

1.470

0.670 (0.251–8.621)

5.468

0.001 (1.916–15.61)*

2.058

0.413 (0.366–11.58)

Wealth quintile

       

Poorest

0.467

0.052 (0.216–1.007)

0.717

0.591 (0.214–2.406)

1.200

0.845 (0.192–7.500)

2.352

0.480 (0.219–25.21)

Poorer

0.898

0.762 (0.447–1.803)

0.702

0.519 (0.239–2.060)

0.898

0.916 (0.121–6.647)

0.862

0.913 (0.059–12.38)

Middle

   

[Reference]

   

[Reference]

Richer

0.467

0.058 (0.213–1.026)

0.629

0.439 (0.195–2.034)

2.588

0.259 (0.497–13.48)

2.579

0.380 (0.311–21.41)

Richest

0.156

0.001 (0.050–0.486)*

0.295

0.175 (0.050–1.725)

8.426

0.006 (1.847–38.43)*

14.25

0.016 (1.638–23.91)*

Household size

        

 < 10 persons

   

[Reference]

   

[Reference]

 ≥ 10 persons

0.357

0.010 (0.163–0.785)*

0.681

0.517 (0. 212–2.181)

0.761

0.568 (0.298–1.943)

0.804

0.752 (0.208–3.110)

Weight gain

        

 < 6 kg

   

[Reference]

   

[Reference]

 ≥ 6 kg

0.499

0.011 (0.292–0.855)*

0.639

0.292 (0.279–1.468)

3.011

0.078 (0.884–10.26)

0.1667

0.066 (0.247–1.124)

Childbirth length

        

 ≤ 47.5 cm

   

[Reference]

   

[Reference]

 > 47.5 cm

0.268

 < 0.001 (0.152–0.473)*

0.271

0.003 (0.113–0.651)*

2.649

0.195 (0.607–11.57)

0.956

0.961 (0.158–5.782)

Number of ANC visits

       

 < 8 visits

   

[Reference]

   

[Reference]

 ≥ 8 visits

0.254

 < 0.001 (0.139–0.464)*

0.249

0.002 (0.103–0.602)*

5.200

0.001 (1.934–13.98)*

0.804

0.752 (0.208–3.110)

ITNs use

        

ITNs use

   

[Reference]

   

[Reference]

No ITNs use

2.788

 < 0.001 (1.658–4.688)*

0.931

0.863 (0.413–2.097)

0.952

0.905 (0.429–2.116)

0.970

0.962 (0.275–3.423)

Number of SP intake

       

None

2.111

0.152 (0.760–5.863)

4.066

0.157 (0.584–28.30)

1.759

0.619 (0.190–16.27)

0.765

0.862 (0.037–15.63)

1–3 doses

   

[Reference]

   

[Reference]

 > 3 doses

0.518

0.016 (0.303–0.886)*

1.470

0.368 (0.635–3.403)

2.676

0.038 (1.054–6.793)*

0.745

0.674 (0.190–2.926)

Gestational age at birth

       

Preterm

3.233

 < 0.001 (1.811–5.771)*

1.548

0.348 (0.621–3.858)

0.892

0.860 (0.250–3.181)

4.980

0.071 (0.873–28.41)

Normal term

   

[Reference]

   

[Reference]

Post-term

0.750

0.714 (0.161–3.495)

2.709

0.502 (0.148–49.71)

10.00

 < 0.001 (3.742–26.72)*

23.21

 < 0.001 (4.603–56.19)*

First-trimester Hb levels

       

Anaemia

8.585

 < 0.001 (4.404–16.74)*

3.226

0.007 (1.372–7.584)*

–

0.974 (–)

–

0.988 (–)

Normal Hb

   

[Reference]

   

[Reference]

Polycythaemia

–

0.997 (–)

–

1.000 (–)

5.852

0.001 (2.139–16.00)*

3.460

0.128 (0.700–17.09)

Second-trimester Hb levels

       

Anaemia

26.17

 < 0.001 (8.038–85.22)*

Dropped due to multicollinearity

0.165

0.001 (0.559–0.489)*

Dropped due to multicollinearity

Normal Hb

 

[Reference]

 

[Reference]

Polycythaemia

–

0.986 (–)

4.964

0.118 (0.667–36.92)

Third-trimester Hb levels

       

Anaemia

36.57

 < 0.001 (12.92–103.5)*

23.94

 < 0.001 (7.442–77.01)*

0.070

0.009 (0.009–0.521)

0.116

0.074 (0.011–1.230)

Normal Hb

   

[Reference]

   

[Reference]

Polycythaemia

–

0.993 (–)

–

0.999 (–)

2.859

0.238 (0.500–16.36)

0.485

0.559 (0.043–5.500)

Gestational diabetes

        

Without diabetes

   

[Reference]

   

[Reference]

With diabetes

–

0.982 (–)

–

0.996 (–)

2.767

0.035 (0.937–8.169)*

1.058

0.941 (0.236–4.738)

Hypertension status

        

Without HPT

   

[Reference]

   

[Reference]

With HPT

1.496

0.301 (0.697–3.211)

2.787

0.161 (0.665–11.67)

3.784

0.003 (1.566–9.146)*

2.581

0.158 (0.692–9.632)

Regression model

        

R2

0.477

       

p value

 < 0.001

       
  1. Bold = significant AOR, p value, and 95%CI for risk factors
  2. AOR, Adjusted odds ratio; COR, Crude odds ratio
  3. *p value < 0.05
  4. ††Bulsa, Dagaati, Ewe, Fulani, Gonja