Skip to main content

Table 3 Serum levels of inflammatory markers and matrix metalloproteinases in patients with knee osteoarthritis across quartiles of dietary TACa

From: Dietary total antioxidant capacity is associated with lower disease severity and inflammatory and oxidative stress biomarkers in patients with knee osteoarthritis

Variables

Quartiles of dietary TACb

P-trendc

Q1 (n = 40)

Q2 (n = 40)

Q3 (n = 40)

Q4 (n = 40)

IL-1β (pg/ml)

14.0 ± 7.5

12.8 ± 5.9

14.7 ± 8.4

13.3 ± 7.0

0.937

IL-6 (pg/ml)

10.8 ± 5.7

10.0 ± 5.7

9.4 ± 4.3

7.8 ± 3.9

0.007

TNF-α (pg/ml)

35.7 ± 6.4

27.5 ± 4.5

25.7 ± 4.4

22.8 ± 3.6

 < 0.001

hs-CRP (mg/l)

5.52 ± 3.55

4.85 ± 2.74

4.91 ± 3.21

4.38 ± 2.51

0.119

NF-кB p65 (arbitrary unit)

1.94 ± 0.64

1.63 ± 0.46

1.71 ± 0.51

1.55 ± 0.54

0.005

MMP-1 (ng/ml)

7.69 ± 3.15

6.22 ± 3.26

6.13 ± 2.67

4.79 ± 2.53

0.001

MMP-3 (ng/ml)

13.6 ± 4.2

12.5 ± 3.1

13.6 ± 4.6

12.3 ± 2.9

0.258

MMP-13 (ng/ml)

0.88 ± 0.58

0.69 ± 0.25

0.80 ± 0.38

0.68 ± 0.30

0.101

  1. TAC, total antioxidant capacity; IL-1β, interleukin-1β; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; hs-CRP, high-sensitivity C-reactive protein; NF-κB p65, nuclear factor-kappa B (p65); MMP-1, matrix metalloproteinase-1; MMP-3, matrix metalloproteinase-3; and MMP-13, matrix metalloproteinase-13
  2. aAll values are expressed as means ± standard deviations
  3. bQuartile cut points of dietary TAC are as follows: first quartile, < 8.02; second quartile, 8.02–11.39; third quartile, 11.40–15.43; and fourth quartile, ≥ 15.44
  4. cResulted from analysis of variance (ANOVA)
  5. P < 0.05 was considered significant
Back to article page

Journal of Health, Population and Nutrition

ISSN: 2072-1315

Contact us