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Table 4 Results of multiple linear regression analyses that evaluated the association between dietary TAC with inflammatory markers and matrix metalloproteinases (n = 160)a

From: Dietary total antioxidant capacity is associated with lower disease severity and inflammatory and oxidative stress biomarkers in patients with knee osteoarthritis

Variables

Dietary TAC

B (S.E.)

β

Pa

IL-1β (pg/ml)

− 0.18 (0.5)

− 0.03

0.724

IL-6 (pg/ml)

− 0.83 (0.35)

− 0.18

0.020

TNF-α (pg/ml)

− 4.07 (0.36)

− 0.67

 < 0.001

hs-CRP (mg/l)

− 0.36 (0.21)

− 0.13

0.093

NF-кB p65 (arbitrary unit)

− 0.11 (0.04)

− 0.22

0.005

MMP-1 (ng/ml)

− 0.91 (0.21)

− 0.33

 < 0.001

MMP-3 (ng/ml)

− 0.41 (0.27)

− 0.12

0.139

MMP-13 (ng/ml)

− 0.05 (0.03)

− 0.12

0.124

  1. TAC, total antioxidant capacity; IL-1β, interleukin-1β; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; hs-CRP, high-sensitivity C-reactive protein; NF-κB p65, nuclear factor-kappa B (p65); MMP-1, matrix metalloproteinase-1; MMP-3, matrix metalloproteinase-3; MMP-13, matrix metalloproteinase-13; B, unstandardized coefficient; and S.E., standard error
  2. aAdjusted for age (continuous), sex (male/ female), BMI (kg/m2), disease duration (continuous), energy intake (kcal/d), vitamin D and calcium supplement use (yes/ no), physical activity level (continuous), and cigarette smoking (smoker/nonsmoker)
  3. P < 0.05 was considered significant