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Table 3 Association between dietary antioxidants intake and childhood eczema in age subgroups

From: Association between dietary antioxidants intake and childhood eczema: results from the NHANES database

Variables

1–5 years old

(n = 312)

6–11 years old

(n = 738)

12–17 years old

(n = 1254)

P for interaction

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

Original data

Vitamin E (mg)

0.97 (0.83–1.14)

0.753

0.95 (0.85–1.06)

0.337

0.95 (0.88–1.02)

0.154

0.979

β-carotene (mcg)

1.01 (1.01–1.01)

0.003

1.00 (1.00–1.00)

0.447

1.00 (1.00–1.00)

0.767

0.150

Vitamin C (mg)

1.00 (0.99–1.01)

0.704

1.00 (0.99–1.00)

0.201

1.00 (1.00–1.00)

0.702

0.633

Zinc (mg)

0.87 (0.76–0.98)

0.027

0.94 (0.88–1.01)

0.091

0.97 (0.93–1.02)

0.216

0.148

Selenium (mcg)

1.00 (0.98–1.01)

0.792

1.00 (0.99–1.01)

0.615

1.00 (1.00–1.01)

0.578

0.527

Retinol (mcg)

1.01 (1.01–1.01)

0.049

1.00 (1.00–1.00)

0.285

1.00 (1.00–1.00)

0.251

0.412

Normalized data

Vitamin E (mg)

0.88 (0.41–1.92)

0.753

0.76 (0.44–1.32)

0.337

0.77 (0.54–1.10)

0.154

 

β-carotene (mcg)

2.12 (1.30–3.47)

0.003

1.09 (0.87–1.36)

0.447

1.03 (0.85–1.24)

0.767

 

Vitamin C (mg)

0.89 (0.50–1.59)

0.704

0.80 (0.58–1.12)

0.201

0.96 (0.77–1.19)

0.702

 

Zinc (mg)

0.38 (0.16–0.90)

0.027

0.66 (0.41–1.07)

0.091

0.83 (0.62–1.11)

0.216

 

Selenium (mcg)

0.89 (0.39–2.05)

0.792

0.89 (0.56–1.41)

0.615

1.09 (0.80–1.48)

0.578

 

Retinol (mcg)

1.79 (1.01–3.21)

0.049

0.84 (0.60–1.16)

0.285

1.14 (0.91–1.43)

0.251

 

Vitamin E

< 3.82

Ref

 

Ref

 

Ref

  

[3.82, 6.28)

0.45 (0.15–1.34)

0.151

0.91 (0.47–1.73)

0.766

1.04 (0.61–1.79)

0.876

 

≥ 6.28

0.52 (0.10–2.67)

0.431

1.73 (0.76–3.94)

0.192

0.86 (0.45–1.67)

0.664

 

P for trend

 

0.442

 

0.254

 

0.818

 

β-carotene

< 230

Ref

 

Ref

 

Ref

  

[230, 613)

1.20 (0.48–2.98)

0.697

0.56 (0.30–1.06)

0.073

0.81 (0.48–1.36)

0.422

 

≥ 613

1.56 (0.62–3.93)

0.342

0.56 (0.29–1.10)

0.091

0.98 (0.57–1.70)

0.956

 

P for trend

 

0.224

 

0.101

 

0.864

 

Vitamin C

< 35.5

Ref

 

Ref

 

Ref

  

[35.5, 96.1)

0.99 (0.37–2.68)

0.990

1.04 (0.58–1.87)

0.892

1.32 (0.81–2.17)

0.266

 

≥ 96.1

1.49 (0.53–4.21)

0.455

0.90 (0.46–1.77)

0.756

0.89 (0.51–1.55)

0.674

 

P for trend

 

0.416

 

0.825

 

0.701

 

Zinc

< 7.47

Ref

 

Ref

 

Ref

  

[7.47, 11.83)

0.31 (0.11–0.86)

0.024

0.45 (0.25–0.83)

0.011

1.34 (0.77–2.32)

0.305

 

≥ 11.83

0.15 (0.04–0.68)

0.013

0.34 (0.16–0.74)

0.007

0.64 (0.31–1.31)

0.226

 

P for trend

 

0.004

 

0.012

 

0.228

 

Selenium

< 68.8

Ref

 

Ref

 

Ref

  

[68.8, 104.4)

0.76 (0.29–2.02)

0.588

0.93 (0.51–1.67)

0.803

0.91 (0.52–1.60)

0.751

 

≥ 104.4

1.30 (0.31–5.45)

0.722

0.67 (0.30–1.48)

0.325

1.38 (0.71–2.67)

0.345

 

P for trend

 

0.868

 

0.200

 

0.283

 

Retinol

< 253

Ref

 

Ref

 

Ref

  

[253, 500)

0.84 (0.32–2.18)

0.714

0.82 (0.44–1.55)

0.547

1.18 (0.72–1.95)

0.511

 

≥ 500

1.91 (0.66–5.52)

0.234

1.31 (0.68–2.55)

0.422

1.36 (0.77–2.39)

0.293

 

P for trend

 

0.294

 

0.406

 

0.318

 
  1. OR Odds ratio, CI Confidence interval, Ref Reference, Vitamin E adjusted for gender, race, family educational background, PIR, insurance, asthma, hay fever, food allergy, BMI, energy intake, PUFA intake, IgE, β-carotene, vitamin C, zinc, selenium, and retinol, β-carotene adjusted for gender, race, family educational background, PIR, insurance, asthma, hay fever, food allergy, BMI, energy intake, PUFA intake, IgE, vitamin E, vitamin C, zinc, selenium, and retinol, Vitamin C Adjusted for gender, race, family educational background, PIR, insurance, asthma, hay fever, food allergy, BMI, energy intake, PUFA intake, IgE, vitamin E, β-carotene, zinc, selenium, and retinol, Zinc Adjusted for gender, race, family educational background, PIR, insurance, asthma, hay fever, food allergy, BMI, energy intake, PUFA intake, IgE, vitamin E, β-carotene, vitamin C, selenium, and retinol, Selenium Adjusted for gender, race, family educational background, PIR, insurance, asthma, hay fever, food allergy, BMI, energy intake, PUFA intake, IgE, vitamin E, β-carotene, vitamin C, zinc, and retinol, Retinol Adjusted for gender, race, family educational background, PIR, insurance, asthma, hay fever, food allergy, BMI, energy intake, PUFA intake, IgE, vitamin E, β-carotene, vitamin C, zinc and selenium