Table 3 Descriptive analysis of OTP admissions and treatment outcomes by protocol

# of sites

61

58

17

28

34

# of records

N = 21,860

n = 10,006

n = 4290

n = 4128

n = 3436

Age at enrollment (months)

n = 21,770

n = 9936

n = 4290

n = 4127

n = 3417

 Median (range)

15 (1.0–59.0)

15 (1.0–59.0)

18 (6.0–59.0)

13 (1.0–58.0)

14 (6.0–59.0)

 < 0.001

 Mean (CI)

17.8 (17.6–17.9)

18.1 (17.9–18.3)

19.5 (19.2–19.9)

15.8 (15.5–16.0)

17.1 (16.8–17.4)

 6–12 months

42.3% (41.7–43.0%)

42.5% (41.6–43.5%)

35.2% (33.8–36.6%)

47.5% (45.9–49.0%)

44.5% (42.8–46.2%)

 < 0.001

 13–24 months

37.5% (36.9–38.1%)

35.8% (34.9–36.7%)

38.8% (37.3–40.2%)

41.4% (39.8–42.9%)

36.2% (34.6–37.8%)

 25–36 months

15.2% (14.7–15.6%)

16.2% (15.5–16.9%)

19.3% (18.1–20.5%)

8.7% (7.8–9.6%)

14.7% (13.5–15.9%)

 37–48 months

4.3% (4.0–4.6%)

4.5% (4.1–4.9%)

5.9% (5.2–6.6%)

2.3% (1.8–2.8%)

4.2% (3.6–4.9%)

 49–59 months

0.7% (0.6–0.8%)

1.0% (0.8–1.2%)

0.8% (0.6–1.1%)

0.2% (0.0–0.3%)

0.4% (0.2–0.6%)

Sex

n = 21,823

n = 10,003

n = 4289

n = 4117

n = 3414

 Female

54.8% (54.1–55.4%)

54.9% (53.9–55.8%)

54.3% (52.8–55.8%)

55.4% (53.8–56.9%)

54.3% (52.7–56.0%)

0.744

 Male

45.2% (44.6–45.9%)

45.1% (44.2–46.1%)

45.7% (44.2–47.2%)

44.6% (43.1–46.2%)

45.7% (44.0–47.3%)

MUAC at Enrollment (mm)

n = 21,812

n = 9961

n = 4288

n = 4128

n = 3435

 Median (range)

112 (70.0–135.0)

112 (70.0–125.0)

112 (71.0–135.0)

112 (83.0–114.0)

112 (84.0–114.0)

 < 0.001

 Mean (CI)

111.2 (111.1–111.2)

111.0 (110.9–111.0)

111.1 (111.0–111.3)

111.3 (111.2–111.4)

111.6 (111.5–111.7)

Change in MUAC from Enrollment to Discharge (mm)

n = 21,798

n = 9954

n = 4284

n = 4125

n = 3435

 Median (range)

6 (− 43.0–46.0)

6 (− 43.0–46.0)

7 (− 22.0–45.0)

5 (− 28.0–41.0)

5 (− 21.0–33.0)

 < 0.001

 Mean (CI)

6.3 (6.2–6.3)

6.4 (6.3–6.4)

7.0 (6.9–7.1)

6.1 (6.0–6.2)

5.4 (5.3–5.6)

Length of stay

n = 18,370

n = 7332

n = 4263

n = 3974

n = 2801

 Median (IQR)

49 (34.0–67.0)

53 (36.0–70.0)

42 (28.0–62.0)

43 (32.0–59.0)

47 (35.0–70.0)

 < 0.001

 Mean (CI)

51.0 (50.7–51.4)

55.3 (54.8–55.9)

45.3 (44.6–46.0)

48.0 (47.3–48.7)

52.7 (51.8–53.7)

Time to recovery*

n = 16,757

n = 6569

n = 3677

n = 3839

n = 2672

 Median (IQR)

49 (35.0–64.0)

53 (37.0–70.0)

42 (28.0–58.0)

42 (32.0–58.0)

47 (35.0–70.0)

 < 0.001

 Mean (CI)

51.1 (50.7–51.4)

55.5 (54.9–56.1)

45.2 (44.5–45.9)

47.8 (47.1–48.5)

52.9 (51.9–53.8)

Exit type

n = 21,860

n = 10,006

n = 4290

n = 4128

n = 3436

 Cured

90.3% (89.9–90.6%)

88.0% (87.4–88.7%)

85.9% (84.9–87.0%)

95.8% (95.2–96.4%)

95.5% (94.8–96.2%)

 < 0.001

 Default

1.8% (1.6–2.0%)

2.5% (2.2–2.8%)

2.2% (1.8–2.6%)

0.4% (0.2–0.5%)

1.1% (0.8–1.5%)

 Death

0.1% (0.0–0.1%)

0.0% (0.0–0.1%)

0.1% (0.0–0.3%)

0.0% (0.0–0.0%)

0.0% (0.0–0.0%)

 Non-response

2.2% (2.0–2.4%)

2.5% (2.2–2.8%)

4.0% (3.4–4.6%)

1.1% (0.8–1.5%)

0.3% (0.1–0.5%)

 Not recovered/ outcome unknown

3.2% (3.0–3.4%)

4.4% (4.0–4.8%)

1.6% (1.2–2.0%)

2.6% (2.1–3.1%)

2.4% (1.9–2.9%)

 Transfer

2.5% (2.3–2.7%)

2.5% (2.2–2.8%)

6.1% (5.4–6.8%)

0.1% (0.0–0.2%)

0.7% (0.4–1.0%)