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Table 3 Multivariable log-binomial regression for the association between body mass index and new-onset of heart failure among Thai patients with hypertension, stratified by blood pressure control for the latest two consecutive visits

From: Association between obesity and new-onset heart failure among patients with hypertension in Thailand

Variables

Control BP

Uncontrol BP

p for interaction

aRR (95% CI)*

p-value

aRR (95% CI)*

p-value

Body mass index (BMI)

     

 Continuous (linear)

1.10 (1.03–1.17)

0.007

1.09 (1.04–1.14)

 < 0.001

0.477

 Continuous (quadratic)

1.002 (1.001–1.002)

0.010

1.001 (1.001–1.002)

 < 0.001

0.763

BMI category, kg/m2

    

0.602

 < 18.50

0.55 (0.12–2.57)

0.447

1.62 (0.41–6.32)

0.490

 

 18.50–22.99

Ref.

 

Ref.

  

 23.00–24.99

1.22 (0.41–3.68)

0.720

1.04 (0.33–3.29)

0.948

 

 25.00–29.99

1.61 (0.62–4.17)

0.327

1.53 (0.59–3.99)

0.382

 

 ≥ 30.00

4.85 (1.77–13.28)

0.002

3.21 (1.17–8.80)

0.024

 

BMI ≥ 25 kg/m2

    

0.642

 No

Ref.

 

Ref.

  

 Yes

2.33 (1.12–4.83)

0.023

1.83 (0.93–3.58)

0.080

 

BMI ≥ 30 kg/m2

    

0.926

 No

Ref.

 

Ref.

  

 Yes

4.05 (1.73–9.51)

0.001

2.52 (1.25–5.06)

0.010

 
  1. BMI body mass index, BP blood pressure, aRR adjusted Risk Ratio, 95% CI 95% confidence interval
  2. *Multivariable analysis: adjusting for age, sex, health schemes, geographic regions, location of outpatient clinic, type 2 diabetes, dyslipidemia, renal insufficiency, history of ischemic heart disease, smoking status, alcohol use, control blood pressure consecutively two latest visits, and ACEI/ARB use